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Proteome-wide detection of S-nitrosylation targets and motifs using bioorthogonal cleavable-linker-based enrichment and switch technique

Cysteine modifications emerge as important players in cellular signaling and homeostasis. Here, we present a chemical proteomics strategy for quantitative analysis of reversibly modified Cysteines using bioorthogonal cleavable-linker and switch technique (Cys-BOOST). Compared to iodoTMT for total Cy...

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Detalles Bibliográficos
Autores principales: Mnatsakanyan, Ruzanna, Markoutsa, Stavroula, Walbrunn, Kim, Roos, Andreas, Verhelst, Steven H. L., Zahedi, René P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522481/
https://www.ncbi.nlm.nih.gov/pubmed/31097712
http://dx.doi.org/10.1038/s41467-019-10182-4