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miR-23b-3p suppressing PGC1α promotes proliferation through reprogramming metabolism in osteosarcoma
Metabolic shift from oxidative phosphorylation (OXPHOS) to glycolysis is a hallmark of osteosarcoma (OS). However, the mechanisms of the metabolic switch have not been completely elucidated. Here we reported that the miR-23b-3p was significantly upregulated in OS cells. Functional studies suggested...
Autores principales: | Zhu, Ran, Li, Xinpan, Ma, Yanhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522531/ https://www.ncbi.nlm.nih.gov/pubmed/31097683 http://dx.doi.org/10.1038/s41419-019-1614-1 |
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