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Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner

The transcription factor Yin Yang 1 (YY1) plays an important role in human disease. It is often overexpressed in cancers and mutations can lead to a congenital haploinsufficiency syndrome characterized by craniofacial dysmorphisms and neurological dysfunctions, consistent with a role in brain develo...

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Detalles Bibliográficos
Autores principales: Zurkirchen, Luis, Varum, Sandra, Giger, Sonja, Klug, Annika, Häusel, Jessica, Bossart, Raphaël, Zemke, Martina, Cantù, Claudio, Atak, Zeynep Kalender, Zamboni, Nicola, Basler, Konrad, Sommer, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522535/
https://www.ncbi.nlm.nih.gov/pubmed/31097699
http://dx.doi.org/10.1038/s41467-019-09823-5