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Lack of selective resistance of influenza A virus in presence of host-targeted antiviral, UV-4B

Development of antiviral drug resistance is a continuous concern for viruses with high mutation rates such as influenza. The use of antiviral drugs targeting host proteins required for viral replication is less likely to result in the selection of resistant viruses than treating with direct-acting a...

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Detalles Bibliográficos
Autores principales: Warfield, Kelly L., Schaaf, Kaitlyn R., DeWald, Lisa Evans, Spurgers, Kevin B., Wang, Wei, Stavale, Eric, Mendenhall, Michelle, Shilts, Meghan H., Stockwell, Timothy B., Barnard, Dale L., Ramstedt, Urban, Das, Suman R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522537/
https://www.ncbi.nlm.nih.gov/pubmed/31097731
http://dx.doi.org/10.1038/s41598-019-43030-y