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c-FLIP and CD95 signaling are essential for survival of renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is the most-prominent tumor type of kidney cancers. Resistance of renal cell carcinoma (RCC) against tumor therapy is often owing to apoptosis resistance, e.g., by overexpression of anti-apoptotic proteins. However, little is known about the role of the apopto...

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Detalles Bibliográficos
Autores principales: Luebke, Tobias, Schwarz, Lisa, Beer, Yan Yan, Schumann, Sabrina, Misterek, Maria, Sander, Frida Ewald, Plaza-Sirvent, Carlos, Schmitz, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522538/
https://www.ncbi.nlm.nih.gov/pubmed/31097685
http://dx.doi.org/10.1038/s41419-019-1609-y