LXRα limits TGFβ-dependent hepatocellular carcinoma associated fibroblast differentiation

Transforming growth factor β (TGFβ) is deposited in the extracellular space of diverse tissues. Resident fibroblasts respond to TGFβ and undergo myofibroblastic differentiation during tissue wound healing and cancer progression. Cancer-associated fibroblasts (CAFs) communicate with tumor cells durin...

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Detalles Bibliográficos
Autores principales: Morén, Anita, Bellomo, Claudia, Tsubakihara, Yutaro, Kardassis, Dimitris, Mikulits, Wolfgang, Heldin, Carl-Henrik, Moustakas, Aristidis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522550/
https://www.ncbi.nlm.nih.gov/pubmed/31097694
http://dx.doi.org/10.1038/s41389-019-0140-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522550/
https://www.ncbi.nlm.nih.gov/pubmed/31097694
http://dx.doi.org/10.1038/s41389-019-0140-4

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