Cyclin-dependent kinase 1-mediated phosphorylation of SET at serine 7 is essential for its oncogenic activity

SE translocation (SET), an inhibitor of protein phosphatase 2A (PP2A), plays important roles in mitosis and possesses oncogenic activity in several types of cancer. However, little is known regarding its regulation. Here we reveal a novel phosphorylation site of SET isoform 1, and we have determined...

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Detalles Bibliográficos
Autores principales: Yin, Ling, Zeng, Yongji, Xiao, Yi, Chen, Yuanhong, Shen, Hong, Dong, Jixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522553/
https://www.ncbi.nlm.nih.gov/pubmed/31097686
http://dx.doi.org/10.1038/s41419-019-1621-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522553/
https://www.ncbi.nlm.nih.gov/pubmed/31097686
http://dx.doi.org/10.1038/s41419-019-1621-2

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