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Cyclin-dependent kinase 1-mediated phosphorylation of SET at serine 7 is essential for its oncogenic activity
SE translocation (SET), an inhibitor of protein phosphatase 2A (PP2A), plays important roles in mitosis and possesses oncogenic activity in several types of cancer. However, little is known regarding its regulation. Here we reveal a novel phosphorylation site of SET isoform 1, and we have determined...
Autores principales: | Yin, Ling, Zeng, Yongji, Xiao, Yi, Chen, Yuanhong, Shen, Hong, Dong, Jixin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522553/ https://www.ncbi.nlm.nih.gov/pubmed/31097686 http://dx.doi.org/10.1038/s41419-019-1621-2 |
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