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Kappa chain maturation helps drive rapid development of an infant HIV-1 broadly neutralizing antibody lineage
HIV-infected infants develop broadly neutralizing plasma responses with more rapid kinetics than adults, suggesting the ontogeny of infant responses could better inform a path to achievable vaccine targets. Here we reconstruct the developmental lineage of BF520.1, an infant-derived HIV-specific broa...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522554/ https://www.ncbi.nlm.nih.gov/pubmed/31097697 http://dx.doi.org/10.1038/s41467-019-09481-7 |