Novel Iodine-induced Cleavage Real-time PCR Assay for Accurate Quantification of Phosphorothioate Modified Sites in Bacterial DNA

DNA Phosphorothioate (PT), replacing a non-bridging phosphate oxygen atom with a sulfur atom, is one kind of common DNA modification in bacteria. Whole genome scale description of the location and frequency of PT modification is the key to understand its biological function. Herein we developed a no...

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Detalles Bibliográficos
Autores principales: Chen, Yi, Zheng, Tao, Li, Jinli, Cui, Jinjie, Deng, Zixin, You, Delin, Yang, Litao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522622/
https://www.ncbi.nlm.nih.gov/pubmed/31097783
http://dx.doi.org/10.1038/s41598-019-44011-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522622/
https://www.ncbi.nlm.nih.gov/pubmed/31097783
http://dx.doi.org/10.1038/s41598-019-44011-x

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