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Development of a stable chemically cross-linked erythropoietin dimer for use in the quality control of erythropoietin therapeutic products
Erythropoietin (EPO) is a glycoprotein hormone which promotes red cell replenishment and is also a global biotherapeutic medicine widely used to treat anaemia resulting, for example, from chemotherapy. Requirements of the European Pharmacopoeia stipulate that the level of dimer must be quantified in...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522647/ https://www.ncbi.nlm.nih.gov/pubmed/30972470 http://dx.doi.org/10.1007/s00216-019-01768-4 |