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The impact of oxidative stress, inflammation, and senescence on the maintenance of immunological memory in the bone marrow in old age

The bone marrow (BM) provides a preferential survival environment for the long-term maintenance of antigen-experienced adaptive immune cells. After the contact with antigens, effector/memory T cells and plasma cell precursors migrate to the BM, in which they can survive within survival niches in an...

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Detalles Bibliográficos
Autores principales: Naismith, Erin, Pangrazzi, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522741/
https://www.ncbi.nlm.nih.gov/pubmed/31018996
http://dx.doi.org/10.1042/BSR20190371