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The impact of oxidative stress, inflammation, and senescence on the maintenance of immunological memory in the bone marrow in old age
The bone marrow (BM) provides a preferential survival environment for the long-term maintenance of antigen-experienced adaptive immune cells. After the contact with antigens, effector/memory T cells and plasma cell precursors migrate to the BM, in which they can survive within survival niches in an...
Autores principales: | Naismith, Erin, Pangrazzi, Luca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522741/ https://www.ncbi.nlm.nih.gov/pubmed/31018996 http://dx.doi.org/10.1042/BSR20190371 |
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