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Structural and functional impact of non-synonymous SNPs in the CST complex subunit TEN1: structural genomics approach
TEN1 protein is a key component of CST complex, implicated in maintaining the telomere homeostasis, and provides stability to the eukaryotic genome. Mutations in TEN1 gene have higher chances of deleterious impact; thus, interpreting the number of mutations and their consequential impact on the stru...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522806/ https://www.ncbi.nlm.nih.gov/pubmed/31028137 http://dx.doi.org/10.1042/BSR20190312 |