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Structural and functional impact of non-synonymous SNPs in the CST complex subunit TEN1: structural genomics approach

TEN1 protein is a key component of CST complex, implicated in maintaining the telomere homeostasis, and provides stability to the eukaryotic genome. Mutations in TEN1 gene have higher chances of deleterious impact; thus, interpreting the number of mutations and their consequential impact on the stru...

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Detalles Bibliográficos
Autores principales: Amir, Mohd., Kumar, Vijay, Mohammad, Taj, Dohare, Ravins, Rehman, Md. Tabish, Alajmi, Mohamed F., Hussain, Afzal, Ahmad, Faizan, Hassan, Md. Imtaiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522806/
https://www.ncbi.nlm.nih.gov/pubmed/31028137
http://dx.doi.org/10.1042/BSR20190312