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Perspectives of small molecule inhibitors of activin receptor-like kinase in anti-tumor treatment and stem cell differentiation

Activin receptor-like kinases (ALKs), members of the type I activin receptor family, belong to the serine/threonine kinase receptors of the transforming growth factor-β (TGF-β) superfamily. ALKs mediate the roles of activin/TGF-β in a wide variety of physiological and pathological processes, ranging...

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Detalles Bibliográficos
Autores principales: Cui, Xueling, Shang, Shumi, Lv, Xinran, Zhao, Jing, Qi, Yan, Liu, Zhonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522871/
https://www.ncbi.nlm.nih.gov/pubmed/31059090
http://dx.doi.org/10.3892/mmr.2019.10209