miR-216a exacerbates TGF-β-induced myofibroblast transdifferentiation via PTEN/AKT signaling

Myofibroblast transdifferentiation is an important feature of cardiac fibrosis. Previous studies have indicated that microRNA-216a (miR-216a) is upregulated in response to transforming growth factor-β (TGF-β) in kidney cells and can activate Smad3; however, its role in myofibroblast transdifferentia...

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Detalles Bibliográficos
Autores principales: Qu, Chuan, Liu, Xin, Ye, Tianxin, Wang, Linglin, Liu, Steven, Zhou, Xingyu, Wu, Gang, Lin, Jian, Shi, Shaobo, Yang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522872/
https://www.ncbi.nlm.nih.gov/pubmed/31059054
http://dx.doi.org/10.3892/mmr.2019.10200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522872/
https://www.ncbi.nlm.nih.gov/pubmed/31059054
http://dx.doi.org/10.3892/mmr.2019.10200

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