Downregulation of microRNA-199a-5p attenuates hypoxia/reoxygenation-induced cytotoxicity in cardiomyocytes by targeting the HIF-1α-GSK3β-mPTP axis

MicroRNAs (miRs) have been identified as critical regulatory molecules in myocardial ischemia/reperfusion injury; however, the exact expression profile of miR-199a-5p in reperfusion injury and the underlying pathogenic mechanisms remain unclear. In the present study, it was revealed that miR-199a-5p...

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Detalles Bibliográficos
Autores principales: Liu, Da-Wei, Zhang, Ya-Nan, Hu, Hai-Juan, Zhang, Pu-Qiang, Cui, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522876/
https://www.ncbi.nlm.nih.gov/pubmed/31059047
http://dx.doi.org/10.3892/mmr.2019.10197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522876/
https://www.ncbi.nlm.nih.gov/pubmed/31059047
http://dx.doi.org/10.3892/mmr.2019.10197

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