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Downregulation of microRNA-199a-5p attenuates hypoxia/reoxygenation-induced cytotoxicity in cardiomyocytes by targeting the HIF-1α-GSK3β-mPTP axis
MicroRNAs (miRs) have been identified as critical regulatory molecules in myocardial ischemia/reperfusion injury; however, the exact expression profile of miR-199a-5p in reperfusion injury and the underlying pathogenic mechanisms remain unclear. In the present study, it was revealed that miR-199a-5p...
Autores principales: | Liu, Da-Wei, Zhang, Ya-Nan, Hu, Hai-Juan, Zhang, Pu-Qiang, Cui, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522876/ https://www.ncbi.nlm.nih.gov/pubmed/31059047 http://dx.doi.org/10.3892/mmr.2019.10197 |
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