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Triptolide inhibits migration and proliferation of fibroblasts from ileocolonic anastomosis of patients with Crohn's disease via regulating the miR-16-1/HSP70 pathway

Anastomotic fibrosis is highly likely to lead to reoperation in Crohn's disease (CD) patients. Triptolide (TPL) is considered to have anti-inflammatory and antifibrotic effects in a variety of autoimmune diseases, including CD. The present study aimed to investigate the effects of TPL on fibrob...

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Detalles Bibliográficos
Autores principales: Chen, Min, Wang, Jin-Min, Wang, Dong, Wu, Rong, Hou, Hong-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522880/
https://www.ncbi.nlm.nih.gov/pubmed/30942423
http://dx.doi.org/10.3892/mmr.2019.10117