Evaluation of the published kinase inhibitor set to identify multiple inhibitors of bacterial ATP-dependent mur ligases

The Mur ligases form a series of consecutive enzymes that participate in the intracellular steps of bacterial peptidoglycan biosynthesis. They therefore represent interesting targets for antibacterial drug discovery. MurC, D, E and F are all ATP-dependent ligases. Accordingly, with the aim being to...

Descripción completa

Detalles Bibliográficos
Autores principales: Hrast, Martina, Rožman, Kaja, Ogris, Iza, Škedelj, Veronika, Patin, Delphine, Sova, Matej, Barreteau, Hélène, Gobec, Stanislav, Grdadolnik, Simona Golič, Zega, Anamarija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522912/
https://www.ncbi.nlm.nih.gov/pubmed/31072165
http://dx.doi.org/10.1080/14756366.2019.1608981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522912/
https://www.ncbi.nlm.nih.gov/pubmed/31072165
http://dx.doi.org/10.1080/14756366.2019.1608981

Ejemplares similares