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Evaluation of the published kinase inhibitor set to identify multiple inhibitors of bacterial ATP-dependent mur ligases
The Mur ligases form a series of consecutive enzymes that participate in the intracellular steps of bacterial peptidoglycan biosynthesis. They therefore represent interesting targets for antibacterial drug discovery. MurC, D, E and F are all ATP-dependent ligases. Accordingly, with the aim being to...
Autores principales: | Hrast, Martina, Rožman, Kaja, Ogris, Iza, Škedelj, Veronika, Patin, Delphine, Sova, Matej, Barreteau, Hélène, Gobec, Stanislav, Grdadolnik, Simona Golič, Zega, Anamarija |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522912/ https://www.ncbi.nlm.nih.gov/pubmed/31072165 http://dx.doi.org/10.1080/14756366.2019.1608981 |
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