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ESX Secretion-Associated Protein C From Mycobacterium tuberculosis Induces Macrophage Activation Through the Toll-Like Receptor-4/Mitogen-Activated Protein Kinase Signaling Pathway

Mycobacterium tuberculosis, as a facultative intracellular pathogen, can interact with host macrophages and modulate macrophage function to influence innate and adaptive immunity. Proteins secreted by the ESX-1 secretion system are involved in this relationship. Although the importance of ESX-1 in h...

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Detalles Bibliográficos
Autores principales: Guo, Qinglong, Bi, Jing, Li, Ming, Ge, Wenxue, Xu, Ying, Fan, Weixing, Wang, Honghai, Zhang, Xuelian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523024/
https://www.ncbi.nlm.nih.gov/pubmed/31134163
http://dx.doi.org/10.3389/fcimb.2019.00158