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Comparing internal and external validation in the discovery of qualitative treatment-subgroup effects using two small clinical trials
In a two-arm randomized trial where both arms receive active treatment (i.e., treatments A and B), often the primary goal is to determine which of the treatments, on average, is more effective. A supplementary objective is to understand possible heterogeneity in the treatment effect by identifying m...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523033/ https://www.ncbi.nlm.nih.gov/pubmed/31193216 http://dx.doi.org/10.1016/j.conctc.2019.100372 |