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Pharmacokinetics and Metabolism of Acetyl Triethyl Citrate, a Water-Soluble Plasticizer for Pharmaceutical Polymers in Rats

Acetyl triethyl citrate (ATEC) is a water-soluble plasticizer used in pharmaceutical plasticized polymers. In this study, the pharmacokinetics and metabolism of ATEC were investigated using liquid chromatography–tandem mass spectrometry (LC–MS/MS) in rats. Plasma protein precipitation with methanol...

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Detalles Bibliográficos
Autores principales: Kim, Hyeon, Ji, Young Seok, Rehman, Shaheed Ur, Choi, Min Sun, Gye, Myung Chan, Yoo, Hye Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523079/
https://www.ncbi.nlm.nih.gov/pubmed/30987254
http://dx.doi.org/10.3390/pharmaceutics11040162