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Mouse Models for Exploring the Biological Consequences and Clinical Significance of PIK3CA Mutations
The phosphatidylinositol 3-kinase (PI3K) pathway is involved in a myriad of cellular signalling pathways that regulate cell growth, metabolism, proliferation and survival. As a result, alterations in the PI3K pathway are frequently associated with human cancers. Indeed, PIK3CA—the gene encoding the...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523081/ https://www.ncbi.nlm.nih.gov/pubmed/31018529 http://dx.doi.org/10.3390/biom9040158 |