Biomarker Discovery for Cytochrome P450 1A2 Activity Assessment in Rats, Based on Metabolomics

Cytochrome P450 1A2 (CYP1A2) is one of the major CYP450 enzymes (CYPs) in the liver, and participates in the biotransformation of various xenobiotics and endogenous signaling molecules. The expression and activity of CYP1A2 show large individual differences, due to genetic and environmental factors....

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Detalles Bibliográficos
Autores principales: Pu, Xiao, Gao, Yiqiao, Li, Ruiting, Li, Wei, Tian, Yuan, Zhang, Zunjian, Xu, Fengguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523085/
https://www.ncbi.nlm.nih.gov/pubmed/31003543
http://dx.doi.org/10.3390/metabo9040077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523085/
https://www.ncbi.nlm.nih.gov/pubmed/31003543
http://dx.doi.org/10.3390/metabo9040077

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