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Biomarker Discovery for Cytochrome P450 1A2 Activity Assessment in Rats, Based on Metabolomics
Cytochrome P450 1A2 (CYP1A2) is one of the major CYP450 enzymes (CYPs) in the liver, and participates in the biotransformation of various xenobiotics and endogenous signaling molecules. The expression and activity of CYP1A2 show large individual differences, due to genetic and environmental factors....
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523085/ https://www.ncbi.nlm.nih.gov/pubmed/31003543 http://dx.doi.org/10.3390/metabo9040077 |