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Cell Internalization in Fluidic Culture Conditions Is Improved When Microparticles Are Specifically Targeted to the Human Epidermal Growth Factor Receptor 2 (HER2)

Purpose: To determine if the specific targeting of microparticles improves their internalization by cells under fluidic conditions. Methods: Two isogenic breast epithelial cell lines, one overexpressing the Human Epidermal Growth Factor Receptor 2 (HER2) oncogene (D492HER2) and highly tumorigenic an...

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Detalles Bibliográficos
Autores principales: Mora-Espí, Inmaculada, Ibáñez, Elena, Soriano, Jorge, Nogués, Carme, Gudjonsson, Thorarinn, Barrios, Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523092/
https://www.ncbi.nlm.nih.gov/pubmed/30978948
http://dx.doi.org/10.3390/pharmaceutics11040177