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NFκB- and MAP-Kinase Signaling Contribute to the Activation of Murine Myeloid Dendritic Cells by a Flagellin A: Allergen Fusion Protein

Fusion proteins incorporating the TLR5-ligand flagellin are currently undergoing clinical trials as vaccine candidates for many diseases. We recently reported a flagellin:allergen fusion protein containing the TLR5-ligand flagellin A (FlaA) from Listeria monocytogenes and the major birch pollen alle...

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Detalles Bibliográficos
Autores principales: Moeller, Tobias, Wolfheimer, Sonja, Goretzki, Alexandra, Scheurer, Stephan, Schülke, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523117/
https://www.ncbi.nlm.nih.gov/pubmed/30991709
http://dx.doi.org/10.3390/cells8040355