Membrane Localization of HspA1A, a Stress Inducible 70-kDa Heat-Shock Protein, Depends on Its Interaction with Intracellular Phosphatidylserine

HspA1A is a cytosolic molecular chaperone essential for cellular homeostasis. HspA1A also localizes at the plasma membrane (PM) of tumor and stressed cells. However, it is currently unknown how this cytosolic protein translocates to the PM. Taking into account that HspA1A interacts with lipids, incl...

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Detalles Bibliográficos
Autores principales: Bilog, Andrei D., Smulders, Larissa, Oliverio, Ryan, Labanieh, Cedra, Zapanta, Julianne, Stahelin, Robert V., Nikolaidis, Nikolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523125/
https://www.ncbi.nlm.nih.gov/pubmed/30999671
http://dx.doi.org/10.3390/biom9040152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523125/
https://www.ncbi.nlm.nih.gov/pubmed/30999671
http://dx.doi.org/10.3390/biom9040152

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