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Membrane Localization of HspA1A, a Stress Inducible 70-kDa Heat-Shock Protein, Depends on Its Interaction with Intracellular Phosphatidylserine
HspA1A is a cytosolic molecular chaperone essential for cellular homeostasis. HspA1A also localizes at the plasma membrane (PM) of tumor and stressed cells. However, it is currently unknown how this cytosolic protein translocates to the PM. Taking into account that HspA1A interacts with lipids, incl...
Autores principales: | Bilog, Andrei D., Smulders, Larissa, Oliverio, Ryan, Labanieh, Cedra, Zapanta, Julianne, Stahelin, Robert V., Nikolaidis, Nikolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523125/ https://www.ncbi.nlm.nih.gov/pubmed/30999671 http://dx.doi.org/10.3390/biom9040152 |
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