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Trehalose Modulates Autophagy Process to Counteract Gliadin Cytotoxicity in an In Vitro Celiac Disease Model

Celiac disease (CD) is a chronic systemic autoimmune disorder that is triggered by the ingestion of gliadin peptides, the alcohol-soluble fraction of wheat gluten. These peptides, which play a key role in the immune response that underlies CD, spontaneously form aggregates and exert a direct toxic a...

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Detalles Bibliográficos
Autores principales: Manai, Federico, Azzalin, Alberto, Morandi, Martina, Riccardi, Veronica, Zanoletti, Lisa, Dei Giudici, Marco, Gabriele, Fabio, Martinelli, Carolina, Bozzola, Mauro, Comincini, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523171/
https://www.ncbi.nlm.nih.gov/pubmed/31013754
http://dx.doi.org/10.3390/cells8040348