Targeting Hedgehog (Hh) Pathway for the Acute Myeloid Leukemia Treatment

The Hedgehog (Hh) pathway, containing the Patched (PTCH) and Smoothened (SMO) multitransmembrane proteins, is the main regulator of vertebrate embryonic development. A non-canonical Hh pathway was recently observed in numerous types of solid cancers and hematological malignancies. Although acute mye...

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Detalles Bibliográficos
Autores principales: Terao, Toshiki, Minami, Yosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523210/
https://www.ncbi.nlm.nih.gov/pubmed/30987263
http://dx.doi.org/10.3390/cells8040312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523210/
https://www.ncbi.nlm.nih.gov/pubmed/30987263
http://dx.doi.org/10.3390/cells8040312

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