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Targeting Hedgehog (Hh) Pathway for the Acute Myeloid Leukemia Treatment
The Hedgehog (Hh) pathway, containing the Patched (PTCH) and Smoothened (SMO) multitransmembrane proteins, is the main regulator of vertebrate embryonic development. A non-canonical Hh pathway was recently observed in numerous types of solid cancers and hematological malignancies. Although acute mye...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523210/ https://www.ncbi.nlm.nih.gov/pubmed/30987263 http://dx.doi.org/10.3390/cells8040312 |