Structure and Dynamics of the EGF Receptor as Revealed by Experiments and Simulations and Its Relevance to Non-Small Cell Lung Cancer

The epidermal growth factor receptor (EGFR) is historically the prototypical receptor tyrosine kinase, being the first cloned and the first where the importance of ligand-induced dimer activation was ascertained. However, many years of structure determination has shown that EGFR is not completely un...

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Detalles Bibliográficos
Autores principales: Martin-Fernandez, Marisa L., Clarke, David T., Roberts, Selene K., Zanetti-Domingues, Laura C., Gervasio, Francesco L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523254/
https://www.ncbi.nlm.nih.gov/pubmed/30959819
http://dx.doi.org/10.3390/cells8040316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523254/
https://www.ncbi.nlm.nih.gov/pubmed/30959819
http://dx.doi.org/10.3390/cells8040316

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