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Single-Molecule Real-Time (SMRT) Full-Length RNA-Sequencing Reveals Novel and Distinct mRNA Isoforms in Human Bone Marrow Cell Subpopulations

Hematopoietic cells are continuously replenished from progenitor cells that reside in the bone marrow. To evaluate molecular changes during this process, we analyzed the transcriptomes of freshly harvested human bone marrow progenitor (lineage-negative) and differentiated (lineage-positive) cells by...

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Detalles Bibliográficos
Autores principales: Deslattes Mays, Anne, Schmidt, Marcel, Graham, Garrett, Tseng, Elizabeth, Baybayan, Primo, Sebra, Robert, Sanda, Miloslav, Mazarati, Jean-Baptiste, Riegel, Anna, Wellstein, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523297/
https://www.ncbi.nlm.nih.gov/pubmed/30934798
http://dx.doi.org/10.3390/genes10040253