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Characterization of Amorphous Solid Dispersion of Pharmaceutical Compound with pH-Dependent Solubility Prepared by Continuous-Spray Granulator

A continuous-spray granulator (CTS-SGR) is a one-step granulation technology capable of using solutions or suspensions. The present research objectives were, (1) to reduce the manufacturing operations for solid dosage formulations, (2) to make amorphous solid dispersion (ASD) granules without pre-pr...

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Detalles Bibliográficos
Autores principales: Tanaka, Ryoma, Hattori, Yusuke, Horie, Yukun, Kamada, Hitoshi, Nagato, Takuya, Otsuka, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523299/
https://www.ncbi.nlm.nih.gov/pubmed/30987131
http://dx.doi.org/10.3390/pharmaceutics11040159