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Characterization of Amorphous Solid Dispersion of Pharmaceutical Compound with pH-Dependent Solubility Prepared by Continuous-Spray Granulator
A continuous-spray granulator (CTS-SGR) is a one-step granulation technology capable of using solutions or suspensions. The present research objectives were, (1) to reduce the manufacturing operations for solid dosage formulations, (2) to make amorphous solid dispersion (ASD) granules without pre-pr...
Autores principales: | Tanaka, Ryoma, Hattori, Yusuke, Horie, Yukun, Kamada, Hitoshi, Nagato, Takuya, Otsuka, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523299/ https://www.ncbi.nlm.nih.gov/pubmed/30987131 http://dx.doi.org/10.3390/pharmaceutics11040159 |
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