Phospholipid-Based Prodrugs for Colon-Targeted Drug Delivery: Experimental Study and In-Silico Simulations

In ulcerative colitis (UC), the inflammation is localized in the colon, and one of the successful strategies for colon-targeting drug delivery is the prodrug approach. In this work, we present a novel phospholipid (PL)-based prodrug approach, as a tool for colonic drug targeting in UC. We aim to use...

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Detalles Bibliográficos
Autores principales: Markovic, Milica, Dahan, Arik, Keinan, Shahar, Kurnikov, Igor, Aponick, Aaron, Zimmermann, Ellen M., Ben-Shabat, Shimon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523355/
https://www.ncbi.nlm.nih.gov/pubmed/30995772
http://dx.doi.org/10.3390/pharmaceutics11040186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523355/
https://www.ncbi.nlm.nih.gov/pubmed/30995772
http://dx.doi.org/10.3390/pharmaceutics11040186

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