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Phospholipid-Based Prodrugs for Colon-Targeted Drug Delivery: Experimental Study and In-Silico Simulations
In ulcerative colitis (UC), the inflammation is localized in the colon, and one of the successful strategies for colon-targeting drug delivery is the prodrug approach. In this work, we present a novel phospholipid (PL)-based prodrug approach, as a tool for colonic drug targeting in UC. We aim to use...
Autores principales: | Markovic, Milica, Dahan, Arik, Keinan, Shahar, Kurnikov, Igor, Aponick, Aaron, Zimmermann, Ellen M., Ben-Shabat, Shimon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523355/ https://www.ncbi.nlm.nih.gov/pubmed/30995772 http://dx.doi.org/10.3390/pharmaceutics11040186 |
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