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Polyelectrolytes in Hot Melt Extrusion: A Combined Solvent-Based and Interacting Additive Technique for Solid Dispersions

Solid dispersions are important supersaturating formulations to orally deliver poorly water-soluble drugs. A most important process technique is hot melt extrusion but process requirements limit the choice of suitable polymers. One way around this limitation is to synthesize new polymers. However, t...

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Detalles Bibliográficos
Autores principales: Ditzinger, Felix, Dejoie, Catherine, Sisak Jung, Dubravka, Kuentz, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523407/
https://www.ncbi.nlm.nih.gov/pubmed/30974771
http://dx.doi.org/10.3390/pharmaceutics11040174