Inhibition of Oncogenic Kinases: An In Vitro Validated Computational Approach Identified Potential Multi-Target Anticancer Compounds

Tumorigenesis in humans is a multistep progression that imitates genetic changes leading to cell transformation and malignancy. Oncogenic kinases play a central role in cancer progression, rendering them putative targets for the design of anti-cancer drugs. The presented work aims to identify the po...

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Detalles Bibliográficos
Autores principales: Ikram, Nazia, Mirza, Muhammad Usman, Vanmeert, Michiel, Froeyen, Matheus, Salo-Ahen, Outi M. H., Tahir, Muhammad, Qazi, Aamer, Ahmad, Sarfraz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523505/
https://www.ncbi.nlm.nih.gov/pubmed/30925835
http://dx.doi.org/10.3390/biom9040124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523505/
https://www.ncbi.nlm.nih.gov/pubmed/30925835
http://dx.doi.org/10.3390/biom9040124

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