Differential Effects of Yeast NADH Dehydrogenase (Ndi1) Expression on Mitochondrial Function and Inclusion Formation in a Cell Culture Model of Sporadic Parkinson’s Disease

Parkinson’s disease (PD) is a neurodegenerative disorder that exhibits aberrant protein aggregation and mitochondrial dysfunction. Ndi1, the yeast mitochondrial NADH dehydrogenase (complex I) enzyme, is a single subunit, internal matrix-facing protein. Previous studies have shown that Ndi1 expressio...

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Detalles Bibliográficos
Autores principales: Cronin-Furman, Emily N., Barber-Singh, Jennifer, Bergquist, Kristen E., Yagi, Takao, Trimmer, Patricia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523508/
https://www.ncbi.nlm.nih.gov/pubmed/30934776
http://dx.doi.org/10.3390/biom9040119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523508/
https://www.ncbi.nlm.nih.gov/pubmed/30934776
http://dx.doi.org/10.3390/biom9040119

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