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In Vitro Gene Delivery in Retinal Pigment Epithelium Cells by Plasmid DNA-Wrapped Gold Nanoparticles

Many rare diseases course with affectation of neurosensory organs. Among them, the neuroepithelial retina is very vulnerable due to constant light/oxidative stress, but it is also the most accessible and amenable to gene manipulation. Currently, gene addition therapies targeting retinal tissue (eith...

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Detalles Bibliográficos
Autores principales: Trigueros, Sònia, B. Domènech, Elena, Toulis, Vasileios, Marfany, Gemma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523520/
https://www.ncbi.nlm.nih.gov/pubmed/30970664
http://dx.doi.org/10.3390/genes10040289