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Recent Advances in Computational Protocols Addressing Intrinsically Disordered Proteins
Intrinsically disordered proteins (IDP) are abundant in the human genome and have recently emerged as major therapeutic targets for various diseases. Unlike traditional proteins that adopt a definitive structure, IDPs in free solution are disordered and exist as an ensemble of conformations. This en...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523529/ https://www.ncbi.nlm.nih.gov/pubmed/30979035 http://dx.doi.org/10.3390/biom9040146 |