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Recent Advances in Computational Protocols Addressing Intrinsically Disordered Proteins

Intrinsically disordered proteins (IDP) are abundant in the human genome and have recently emerged as major therapeutic targets for various diseases. Unlike traditional proteins that adopt a definitive structure, IDPs in free solution are disordered and exist as an ensemble of conformations. This en...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Supriyo, Lin, Xingcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523529/
https://www.ncbi.nlm.nih.gov/pubmed/30979035
http://dx.doi.org/10.3390/biom9040146