Engineering ‘designer’ glycomodules for boosting recombinant protein secretion in tobacco hairy root culture and studying hydroxyproline‐O‐glycosylation process in plants

The key technical bottleneck for exploiting plant hairy root cultures as a robust bioproduction platform for therapeutic proteins has been low protein productivity, particularly low secreted protein yields. To address this, we engineered novel hydroxyproline (Hyp)‐O‐glycosylated peptides (HypGPs) in...

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Detalles Bibliográficos
Autores principales: Zhang, Ningning, Wright, Tristen, Wang, Xiaoting, Karki, Uddhab, Savary, Brett J., Xu, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523594/
https://www.ncbi.nlm.nih.gov/pubmed/30467956
http://dx.doi.org/10.1111/pbi.13043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523594/
https://www.ncbi.nlm.nih.gov/pubmed/30467956
http://dx.doi.org/10.1111/pbi.13043

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