Modelling the Effect of Process Parameters on the Wet Extrusion and Spheronisation of High-Loaded Nicotinamide Pellets Using a Quality by Design Approach

The aim of the present study was to develop an alternative process to spray granulation in order to prepare high loaded spherical nicotinamide (NAM) pellets by wet extrusion and spheronisation. Therefore, a quality by design approach was implemented to model the effect of the process parameters of t...

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Detalles Bibliográficos
Autores principales: Theismann, Eva-Maria, K. Keppler, Julia, Owen, Martin, Schwarz, Karin, Schlindwein, Walkiria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523633/
https://www.ncbi.nlm.nih.gov/pubmed/30939803
http://dx.doi.org/10.3390/pharmaceutics11040154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523633/
https://www.ncbi.nlm.nih.gov/pubmed/30939803
http://dx.doi.org/10.3390/pharmaceutics11040154

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