Design of Poly(lactic-co-glycolic Acid) (PLGA) Nanoparticles for Vaginal Co-Delivery of Griffithsin and Dapivirine and Their Synergistic Effect for HIV Prophylaxis

Long-acting topical products for pre-exposure prophylaxis (PrEP) that combine antiretrovirals (ARVs) inhibiting initial stages of infection are highly promising for prevention of HIV sexual transmission. We fabricated core-shell poly(lactide-co-glycolide) (PLGA) nanoparticles, loaded with two potent...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Haitao, Li, Jing, Patel, Sravan Kumar, Palmer, Kenneth E., Devlin, Brid, Rohan, Lisa C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523646/
https://www.ncbi.nlm.nih.gov/pubmed/30995761
http://dx.doi.org/10.3390/pharmaceutics11040184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523646/
https://www.ncbi.nlm.nih.gov/pubmed/30995761
http://dx.doi.org/10.3390/pharmaceutics11040184

Ejemplares similares