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Design of Poly(lactic-co-glycolic Acid) (PLGA) Nanoparticles for Vaginal Co-Delivery of Griffithsin and Dapivirine and Their Synergistic Effect for HIV Prophylaxis

Long-acting topical products for pre-exposure prophylaxis (PrEP) that combine antiretrovirals (ARVs) inhibiting initial stages of infection are highly promising for prevention of HIV sexual transmission. We fabricated core-shell poly(lactide-co-glycolide) (PLGA) nanoparticles, loaded with two potent...

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Detalles Bibliográficos
Autores principales:	Yang, Haitao, Li, Jing, Patel, Sravan Kumar, Palmer, Kenneth E., Devlin, Brid, Rohan, Lisa C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523646/ https://www.ncbi.nlm.nih.gov/pubmed/30995761 http://dx.doi.org/10.3390/pharmaceutics11040184

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