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MicroRNAs Mediated Regulation of Expression of Nucleoside Analog Pathway Genes in Acute Myeloid Leukemia

Nucleoside analog, cytarabine (ara-C) is the mainstay of acute myeloid leukemia (AML) chemotherapy. Cytarabine and other nucleoside analogs require activation to the triphosphate form (ara-CTP). Intracellular ara-CTP levels demonstrate significant inter-patient variation and have been related to the...

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Detalles Bibliográficos
Autores principales: Bhise, Neha S., Elsayed, Abdelrahman H., Cao, Xueyuan, Pounds, Stanley, Lamba, Jatinder K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523677/
https://www.ncbi.nlm.nih.gov/pubmed/31022985
http://dx.doi.org/10.3390/genes10040319